CoQ10 and Statin Drugs
Monday, October 16th 2006
It is well known that statin drugs, used to reduce cholesterol, seriously deplete the body of Coenzyme Q10, a nutrient that is not only heart protective but also important for breast cancer protection in women. Researchers believe women on long term use of statin medications may have a higher risk of developing breast cancer.
Thousands of New Zealanders as millions of people worldwide take statin drugs to reduce cholesterol. All of the statins, Lipitor, Zocor, Mevacor, Pravachol, Lovacol, etc., inhibit CoQ10 production in the body (and transport, it is believed by some researchers, including Dr. Bliznakov) and thus are a threat to good health in general and to heart health in particular.
According to Emile G. Bliznakov, MD and CoQ10 researcher, "I unearthed an important aspect of this story within two statin patents. Two U.S. patents were granted to Merck (the Pharmaceutical Company) in 1990 describing a method for counteracting the statin-associated myopathy and potential nerve damage caused by statins. The method described was the addition of CoQ10 to compensate for the reduced production of CoQ10 caused by the statins. Thus the manufacturer implicated the serious side effects of statins and the protective role played by CoQ10 in preventing these statin side-effects. The manufacturer has not disseminated this data, which seriously incriminates them."
CoQ10 and breast cancer
A deficiency of coenzyme Q10 has been described in aging, cancer and when statin cholesterol-lowering drugs are employed. [J Am Coll Nutr 20: 591-98, 2001]
For example, CoQ10 levels in tissues of breast cancer patients are significantly decreased compared to surrounding tissues. [Clin Biochem 33: 279-84, 2000]. Breast cancer patients are more likely to exhibit low CoQ10 levels than healthy people. [Biochem Biophys Rres Commun 234: 296-99, 1997].
The provision of supplemental CoQ10 (390mg) to breast cancer patients has been shown to induce complete regression in some cases. [Biochem Biophys Res Comm 199: 1504-08, 1994; 212: 172-77, 1995]. Though only a small group study, the provision of an array of antioxidant supplements including coenzyme Q10 to high risk breast cancer patients has been demonstrated to be beneficial in reducing mortality, spread of cancer and providing better quality of life. [Mol Aspects Med 15: 231-40S, 1994].
Reproduced unabridged from the October - December 2006 issue of Health and Herbal News, with the kind permission of Health and Herbs International Ltd.
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