Pomegranate & Cancer Growth
Tuesday, October 10th 2006
In 2006, Michael Aviram, D.Sc, Professor of Biochemistry and Head Lipid Research Laboratory, Technion Faculty of Medicine and Rambam Medical Center, Haifa, Israel led a study which was recently published (Journal of Agriculture and Food Chemistry, 2006 54:1928-1935). Commenting on this research, Professor Aviram remarks, "The results showed that powdered pomegranate is as potent an antioxidant as pomegranate juice and just like pomegranate juice, may protect against cardiovascular and other diseases."
Pomegranate juice is known to have anti-inflammatory effects and high levels of anti-oxidants, which are believed to protect the body from free-radical damage. It also contains polyphenols, natural antioxidant compounds commonly found in green tea, as well as isoflavones commonly found in soy, and ellagic acid, which are believed to play a role in cancer cell death.
Drinking 237ml of pomegranate juice daily increased by nearly four times the period during which PSA levels in men treated for prostate cancer remained stable, a three-year UCLA study has found.
UCLA researchers measured "doubling time," how long it takes for PSA levels to double, a signal that the caner is progressing, said Dr. Allan Pantuck, an associate professor of urology, a Jonsson Cancer Center researcher and lead author of the study. The average doubling time is about 15 months. In the UCLA study, Pantuck and his team observed increases in doubling times from 15 months to 54 months, an almost four-fold increase.
"In older men 65 to 70, who have been treated for prostate cancer, we can give them pomegranate and it may be possible for them to outlive their risk of dying from their cancer. We're hoping we may be able to prevent or delay the need for other therapies usually used in this population group such as hormone treatment or chemotherapy, both of which bring harmful side effects with them."
The study appears in the July 1 issue of Clinical Cancer Research, the peer-reviewed journal of the American Association of Cancer Research.
The levels of PSA in men immediately following treatment should be undetectable, Pantuck said. If PSA can be detected, it's an indication of an aggressive cancer that is likely to progress. Of the 50 men enrolled, more than 80 percent experienced improvement in doubling times.
Conventional treatment for men with recurrent prostate cancer includes hormonal therapy. Men treated with hormonal therapy can experience hot flushes, osteoporosis, fatigue, depression, muscle wasting, loss of libido and erectile dysfunction. If pomegranate can delay or prevent the need for hormonal therapy, patients would experience a better quality of life for a longer time, Pantuck said.
The patients in Pantuck's study experienced no side effects and none of the participants had cancers that metastasized during the study.
Pantuck said he has men on the study more than three years out who are not being treated for prostate cancer other than pomegranate and their PSA levels continue to be suppressed.
Nature's Way Pomegranate contains a whole fruit extract.
Reproduced unabridged from the October - December 2006 issue of Health and Herbal News, with the kind permission of Health and Herbs International Ltd.
Footnote from Ideal Health:
The following products are all useful for Cancer :
Related health information can be found here:
Acid and alkaline forming foods
Active UMF manuka honey - wound healer
Common foods that could be a problem
Foods to help detoxification
FOS - prebiotic food
Green Tea as a medicinal beverage
The Good Health Diet
Water, the elixir of life
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