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White Blood Cell Count Predicts All-Cause Mortality in Heart Disease Patients

White Blood Cell Count Predicts All-Cause Mortality in Heart Disease Patients

Saturday, February 28th 2004

In patients with coronary heart disease (CHD), an elevated white blood cell (WBC) count is tied to a higher risk of all-cause mortality, Israeli researchers report. The excess mortality risk, however, is not due to cardiac causes.

Previous studies have yielded conflicting results regarding a link between WBC count and coronary risk. Many studies that have shown a positive association have not accounted for other coronary risk factors that may have had a confounding effect, lead author Dr. Moti Haim, from the Rabin Medical Center in Petah Tikva, and colleagues note.

As reported in the Archives of Internal Medicine for February 23, Dr. Haim's team investigated the association between WBC count and long-term risk of mortality and coronary events in 3090 patients with CHD. The average follow-up period was 6.2 years.

On initial analysis, the WBC count was a significant predictor of myocardial infarction, cardiac death, and total mortality. However, after adjusting for other risk factors, only a significant association with total mortality remained, the researchers note.

Patients with a WBC count of greater than 7340/microliter had a 47% higher risk of total death than subjects with count of less than 5970/microliter. For every 1000/microliter rise in the WBC count, the risk of total mortality rose by 6%.

"Whether WBC count is a nonspecific marker of increased mortality risk or a marker of long-term mortality from specific causes requires further evaluation," the authors state.

Archives of International Medicine 2004;164:433-439.

Footnote from Ideal Health:

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Opti CoQ10 150mg
Mega Strength Beta Sitosterol
Cayenne Pepper
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Related health information can be found here:

Blood Pressure (High)
Blood Pressure (Low)
Cardiovascular Health
Cayenne - circulatory stimulant
Fish Oil, garlic, antioxidants
Heartburn
Heart Problems
Magnesium
Myocardial Infarction
The Good Health Diet

Related articles can be found here:

High fruit, vegetable intake associated with lower stroke risk
Hot Tea Much Healthier Than a Warm Cuppa
One Drink a Day Improves Overall Cardiovascular Health

If you need help or advice, you are welcome to email our naturopathic team with your health question.

Disclaimer: The health information presented here has been written for the New Zealand health consumer. It is of a general nature and is only intended to provide a summary of the subjects covered. The information is not intended to be comprehensive or to provide medical advice to you. While all care has been taken to ensure the accuracy of the information, no responsibility or liability is accepted, and no person should act in reliance on any statement contained in the information provided. All health ailments should be treated by a qualified health professional.

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