White Blood Cell Count Predicts All-Cause Mortality in Heart Disease Patients
Saturday, February 28th 2004
In patients with coronary heart disease (CHD), an elevated white blood cell (WBC) count is tied to a higher risk of all-cause mortality, Israeli researchers report. The excess mortality risk, however, is not due to cardiac causes.
Previous studies have yielded conflicting results regarding a link between WBC count and coronary risk. Many studies that have shown a positive association have not accounted for other coronary risk factors that may have had a confounding effect, lead author Dr. Moti Haim, from the Rabin Medical Center in Petah Tikva, and colleagues note.
As reported in the Archives of Internal Medicine for February 23, Dr. Haim's team investigated the association between WBC count and long-term risk of mortality and coronary events in 3090 patients with CHD. The average follow-up period was 6.2 years.
On initial analysis, the WBC count was a significant predictor of myocardial infarction, cardiac death, and total mortality. However, after adjusting for other risk factors, only a significant association with total mortality remained, the researchers note.
Patients with a WBC count of greater than 7340/microliter had a 47% higher risk of total death than subjects with count of less than 5970/microliter. For every 1000/microliter rise in the WBC count, the risk of total mortality rose by 6%.
"Whether WBC count is a nonspecific marker of increased mortality risk or a marker of long-term mortality from specific causes requires further evaluation," the authors state.
Archives of International Medicine 2004;164:433-439.
Footnote from Ideal Health:
The following products are all useful for Cardiovascular Health:
Opti CoQ10 150mg
Mega Strength Beta Sitosterol
Garlicin - Cholesterol Control
Hi Strength Liquid Fish Oil
Ultimate Omega + CoQ10
Related health information can be found here:
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Cayenne - circulatory stimulant
Fish Oil, garlic, antioxidants
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