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NSAIDs tied to Non-Hodgkin Lymphoma risk in Women

NSAIDs tied to Non-Hodgkin Lymphoma risk in Women

Saturday, September 13th 2003

Use of nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin, appears to be associated with a heightened risk of non-Hodgkin lymphoma (NHL), according to a study of more than 27,000 postmenopausal women.

In the September 20th issue of the International Journal of Cancer, Dr. James R. Cerhan of the Mayo Clinic, Rochester, Minnesota, and colleagues note that research in patients with rheumatoid arthritis suggest that NSAIDs are protective against colon cancer but may raise the risk of NHL.

To investigate, the team prospectively studied a cohort of 27,290 postmenopausal women participating in the Iowa Women's Health Study, using data from a questionnaire and a state cancer registry to calculate risks.

Over a follow-up period of 7 years, a total of 131 case of NHL were identified.

Compared with women who did not use NSAIDs at all, the NHL risk ratio for those who used aspirin exclusively was 1.71. For those who used non-aspirin NSAIDs exclusively, the risk ratio was 2.39. The corresponding figure for women who used both types of drugs was 1.97.

A diagnosis of rheumatoid arthritis carried a risk ratio of 1.75, but there was no significant relationship with osteoarthritis (risk ratio 1.06). Furthermore, the association of NSAIDs use and NHL was independent of a history of rheumatoid arthritis.

In comments to Reuters Health, Dr. Cerhan observed that "our findings are provocative as they do raise safety concerns about regular use of these agents. However, our findings need to be replicated in additional studies before making any clinical or public health recommendations."

Sourced from the International Journal of Cancer 2003;106:784-788

Footnote from Ideal Health:

The following supplements are all Natural Anti-Inflammatory products:

Back Pain Control
Collagen Type 2 Joint Complex + Hyaluronic acid
Hi Strength Liquid Fish Oil
Joint Vitality
Fish Oil 1000 - Omega 3
Emu Spirit 100% Pure Emu oil
Magnesium Complex Plus
Reflux-free Salmon Oil
Pain Relief
Flax Boost Capsules
Superior Magnesium
Waihi Bush Flax Balance Oil

Related health information can be found here:

Anti Inflammatory
Arthritis & Rheumatism
Carpel Tunnel
Circulatory Problems
Nutritional pain control - DLPA - a powerful pain reliever
Neuromuscular system and nutritional support
Water, the elixir of life

Related articles can be found here:

Arthritis studies focus on Boswellia
Boswellia - rediscovering a powerful anti-inflammatory herb
New Emu Oil Range from Emu Spirit
Danger Warning on Pain Medicine
Efamarine - help for joint mobility and the maintenance of immunity
Turmeric - more than culinary
Understand Why You Hurt All Over - the Benefits of Malic Acid

If you need help or advice, you are welcome to email our naturopathic team with your health question.

Disclaimer: The health information presented here has been written for the New Zealand health consumer. It is of a general nature and is only intended to provide a summary of the subjects covered. The information is not intended to be comprehensive or to provide medical advice to you. While all care has been taken to ensure the accuracy of the information, no responsibility or liability is accepted, and no person should act in reliance on any statement contained in the information provided. All health ailments should be treated by a qualified health professional.


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