Glucosamine 1500 Complex

Brand

Microgenics

Size

180 Tablets

Common Uses

Arthritis, Osteoarthritis, Sporting injuries to the joints, general wear and tear to the joints of the body. Who Would Benefit From Taking Glucosamine? Anyone suffering from an arthritic condition such as Rheumatoid and Osteoarthritis. As well as this anyone recovering from an injury, after an operation and during recuperation, sciatica and disc problems. It can also be useful for athletes as a preventive in case of overuse of joints, heavy lifting and because of the repetitive nature of some sports. Early trials used Glucosamine for inflammatory disorders of the gastrointestinal tract, including ulcerative colitis, Crohn's disease and irritable bowel. Glucosamine sulphate is 95% absorbable when given orally and 30% of the oral dose is retained by the musculoskeletal system for long time periods. It stimulates proteoglycan synthesis in cartilage and other connective tissue. It is the preferred precursor for proteoglycan synthesis including Chondroitin sulphate and hyaluronic acid. Hyaluronic acid, the central organising molecule of the proteoglycan and the major component of the cartilage/synovial membrane interface is 50% glucosamine. Taking this supplement will help to give your body the ingredients to make new cartilage, to help in the repair of cartilage, ligament and tendon damage.

Suggested Dosage

Initially, take two tablets daily for 6-8weeks. Once symptoms have improved, you could reduce the dose to 1 tablet per day.

Health Information

The Use's of Glucosamine. Considerable media attention has been focused on this natural product to help with the pain and stiffness associated with Osteoarthritis. Doctors often recommend aspirin and nonsteroidal anti-inflammatory drugs (NSAID's), but these usually create serious side effects and only offer short term symptom relief. Glucosamine was trialed in Europe in the 1980's and was found to be more effective in reducing joint pain, joint tenderness and joint swelling. Joint function and physical performance always improved. Findings were observed after 4 to 10 weeks of Glucosamine administration. In these studies 1500 mg per day were used. The results were so convincing that Glucosamine has become a first line treatment for osteoarthritis in several European countries. What is Glucosamine and how does it work? Glucosamine is classified as an amino sugar and is incorporated into the structure of body tissues, rather than being used as an energy source. Glucosamine is thus involved in the formation of the nails, tendons, skin, eyes, bones, ligaments and heart valves. It also plays a role in the mucous secretions of the digestive, respiratory and urinary tracts. To understand the mechanism of Glucosamine action we need to look at the biochemistry of the connective tissue that makes up our ligaments, cartilages, tendons and spinal discs. There are 2 main components of these tissues. The first is collagen. The second is a long chain made up mainly of sugars called Glucosaminoglycans (GAG's). These GAG's are the tissue framework that collagen holds onto. Collagen and GAG's together continuously construct and reconstruct our tendons and ligaments. This is where Glucosamine comes in. Glucosamine is the major precursor of GAG's. But even more importantly, the making of Glucosamine from glucose and glutamine is our body's rate-limiting step in remodelling our connective tissue. Following connective tissue injury, such as a cartilage tear, this limit does not allow the body to make sufficient Glucosamine for optimal healing. As we age, the bodies ability to convert glucose and glutamine to Glucosamine declines because of reductions in the level of the converting enzyme Glucosamine synthetase. This is where taking a Glucosamine supplement comes in. Taking a glucosamine supplement can increase GAG levels by up to 170% .

Ingredients

Each Tablet contains: Glucosamine Sulfate (Potassium chloride complex) 1.5g (1500mg), Chondroitin Sulfate 100mg, Proline 50mg, Zingiber officinale (Ginger) ext equiv root dry 200mg.

Safety Information

Keep out of reach of Children. Glucosamine is derived from shrimp & crab shells. Do not use if you have an allergy to these substances or to shellfish.